The science

Sleep isn't rest. It's the operating system.

A searchable evidence library across the sleep health landscape. Every article is labeled with the strength of its underlying evidence.

Overnight hypnogram
  • CBT-IStrong evidence

    CBT-I as first-line for chronic insomnia

    Consistently recommended in clinical guidelines; multiple randomized trials and meta-analyses.

  • CBT-IStrong evidence

    Stimulus control instructions

    Core CBT-I component; robust evidence for reducing sleep-onset latency.

  • InsomniaStrong evidence

    Sleep restriction therapy

    Effective for chronic insomnia; requires clinician oversight for daytime safety.

  • PAP TherapyStrong evidence

    CPAP for moderate-to-severe OSA

    Gold standard therapy; strong evidence for symptom and cardiovascular outcomes with adherence.

  • Circadian RhythmModerate evidence

    Circadian misalignment & metabolic health

    Consistent observational data; mechanistic support; ongoing trials.

  • ChronobiologyStrong evidence

    Light exposure timing and phase shift

    Well-characterized human phase response to light.

  • WearablesEmerging evidence

    Consumer wearable sleep staging accuracy

    Improving, but variance across devices; useful for trends, not diagnosis.

  • Digital TherapeuticsStrong evidence

    Digital CBT-I platforms

    Randomized trials support digital CBT-I for insomnia symptoms.

  • Mental Health & SleepModerate evidence

    Sleep and depression bidirectionality

    Strong association; some evidence sleep treatment improves mood outcomes.

  • Women's Sleep HealthModerate evidence

    Perimenopause and sleep architecture

    Consistent observational data; treatment options vary in evidence strength.

  • Pediatric SleepStrong evidence

    Adolescent phase delay

    Well-established biological delay in adolescence; school start time evidence.

  • Aging & SleepStrong evidence

    Sleep architecture changes with age

    Reduced slow-wave sleep with age is well-characterized.

  • Sleep HygieneEmerging evidence

    Blue-light blocking glasses for sleep

    Mixed evidence; behavioral cues may matter more than spectral filtering.

  • Sleep HygieneEmerging evidence

    Weighted blankets for insomnia

    Small trials suggest benefit for anxiety-related sleep issues.

  • Sleep ApneaModerate evidence

    OSA screening in primary care

    Validated screening tools exist; systematic screening evidence is evolving.

  • ChronobiologyUnknown evidence

    Precision chronotyping from home data

    Active area of investigation; MyRemD is contributing.

How we label evidence

Four levels of certainty.

Strong evidence

Multiple RCTs, meta-analyses, guidelines.

Moderate evidence

Consistent observational data or a single high-quality trial.

Emerging evidence

Early studies; plausible mechanism.

Unknown evidence

Evidence is thin; we say so.